Smarter technologies for finding and selecting better sperm

NeoGenix Fertility develops AI and microfluidic platforms that enhance sperm identification and selection, improving IVF efficiency and accuracy by combining clinical expertise with engineering.

Developed with embryologists, surgeons and leading IVF clinics
Our mission

Bringing clarity and precision to male-factor infertility

For too many couples, male-factor infertility remains a hidden challenge. We build intelligent, evidence-based tools that give IVF laboratories faster, more consistent, and biologically-inspired ways to identify and isolate the best sperm.

Our technologies

Two platforms, one goal: better sperm selection

From passive microfluidic isolation to real-time AI detection, our tools slot into existing lab workflows without adding complexity.

Microfluidics

SpermGuide

A channel-based device that replicates the natural journey of sperm through the female reproductive tract, passively selecting highly-motile sperm with low DNA fragmentation. No centrifugation, no processing stress, no operator bias.

  • Operates over a 15 to 30 minute window
  • Compatible with any sperm-suitable buffer or medium
  • Reduces DNA fragmentation in pre-clinical studies
Learn more
AI software

SpermSearch.AI

An embryologist's co-pilot that identifies potential sperm forms in real time during difficult searches. It accelerates locating rare sperm in mTESE and cryptozoospermic samples, improving efficiency without altering clinical decision-making.

  • Detects sperm forms from testicular tissue and semen
  • Reduces search times by accelerating detection
  • Integrates into existing laboratory workflows
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Pre-clinical & clinical evidence

Built on peer-reviewed science

SpermSearch.AI

Real-time AI-assisted rare-sperm localisation for ICSI
Clinical pilot
41%
less time to search each dish (35.8 to 21.8 min) with AI assistance
Goss et al., Reprod. Biomed. Online (in press)
Clinical pilot
1.8×
more sperm recovered per dish vs unassisted searching
Goss et al., Reprod. Biomed. Online (in press)
Clinical pilot
8 / 40
ICSI cycles used sperm found only with AI assistance
Goss et al., Reprod. Biomed. Online (in press)
Pre-clinical
92%
sperm recall, vs 86.5% for manual searching on still images
Goss et al. 2024, Reprod. Biomed. Online

SpermGuide

Biomimetic microfluidic sperm selection
Pre-clinical
68%
more motile sperm vs previously reported channel methods
Vasilescu et al. 2023, Nat. Microsyst. Nanoeng.
Pre-clinical
85%
improvement in sperm DNA integrity vs swim-up
Vasilescu et al. 2023, Nat. Microsyst. Nanoeng.
Pre-clinical
90%
reduction in sperm apoptosis vs swim-up
Vasilescu et al. 2023, Nat. Microsyst. Nanoeng.
Pre-clinical
92% vs 57%
average DNA fragmentation reduction, microfluidic vs DGC
Vasilescu et al. 2025, Reprod. Biomed. Online
Published in Reproductive BioMedicine Online and Nature Microsystems & Nanoengineering. See the full publications.
Research Use Only collaborations

Developed with embryologists and doctors, translating research into practice

NeoGenix partners with leading IVF clinics to gather critical user feedback. These collaborations ensure our technologies are assessed for practical, real-world use in the IVF lab environment.

1

Co-designed with andrologists, embryologists and surgeons working in IVF labs.

2

Evaluated side-by-side against density gradient centrifugation and swim-up methods in pre-clinical studies.

3

Refined through clinical feedback under Research Use Only conditions.

In their words

What the field is saying

"Knowing that the samples from my surgeries are searched using SpermSearch.AI gives me real peace of mind. It adds an extra layer of thoroughness to the process, and that consistency matters enormously for my patients."

Dr Shannon Hee Kyung Kim
Urological Surgeon, Sydney, Australia

"AI in IVF has focused on the egg and embryo, while a major challenge in the laboratory, finding sperm in severe male factor cases, went overlooked. SpermSearch.AI changes that. The pre-clinical promise was exciting, and the clinical results are even more so. For these patients, it is a real step forward."

Professor David K. Gardner, AM, FAA
Scientific, Innovation and Research Director, Virtus Health

"SpermSearch.AI is an excellent copilot that serves as a second verifier to my own searches and increases my ability to be thorough without extending my search time."

Chaya Rothschild
Senior Andrologist, Maze Mens Health, New York

"A man can make 1500 sperm a second, or over 500 billion sperm in a lifetime. So how can we find the best ones, that lead to a healthy baby? New technologies are needed to find those sperm."

Dr Gavin Sacks
MA BM DPhil FRCOG FRANZCOG, Genea, Sydney, Australia

Modernising sperm processing and isolation

Whether you run an IVF clinic, potential collaborator or investor, we would love to talk about how NeoGenix can help.